The third seminar of the Heart, Lung and Vascular Institute and Cardiovascular Center 2014-15 Seminar Series will be presented on Monday, November 10, from 12 noon – 1 pm in the Medical Sciences Building, 3rd Floor, Room 3351. Lunch will be served at 11:45 am.
Jerry Lingrel, Ph.D., Professor and Interim Chair; Distinguished Research Professor, Dept. of Molecular Genetics, Biochemistry & Microbiology, will present, Role of the KLF2 Transcription Factor in Atherosclerosis. The Lingrel laboratory has been studying a transcription factor, KLF2, which they discovered several years ago.
This transcription factor plays a role in a number of biological processes. Their current studies involve the role of KLF2 in atherosclerosis. These studies show that KLF2 upregulates anti-inflammatory pathways and protects against atherosclerosis. These pathways include cytokine and chemokine pathways and the involvement of specific miRNAs.