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Heart, Lung and Vascular Institute and Cardiovascular Center 2014-15 Seminar Series
Date: Monday, Nov. 10, 2014
Time: Noon - 1 p.m.
Location: Medical Sciences Building, 3rd Floor, Room 3351

Description:


The third seminar of the Heart, Lung and Vascular Institute and Cardiovascular Center 2014-15 Seminar Series will be presented on Monday, November 10, from 12 noon 1 pm in the Medical Sciences Building, 3rd Floor, Room 3351.  Lunch will be served at 11:45 am.

Jerry Lingrel, Ph.D., Professor and Interim Chair; Distinguished Research Professor, Dept. of Molecular Genetics, Biochemistry & Microbiology, will present, Role of the KLF2 Transcription Factor in Atherosclerosis.  The Lingrel laboratory has been studying a transcription factor, KLF2, which they discovered several years ago.

This transcription factor plays a role in a number of biological processes. Their current studies involve the role of KLF2 in atherosclerosis. These studies show that KLF2 upregulates anti-inflammatory pathways and protects against atherosclerosis. These pathways include cytokine and chemokine pathways and the involvement of specific miRNAs.

 




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