UC HealthNews : Sohaib Khan


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Sohaib Khan, PhD, is a professor of cell and cancer biology.

Sohaib Khan

Specialty:	Cancer and Cell Biology
Sub-Specialty:	Hormonal Carcinogenesis
Department:	Cancer and Cell Biology
Title:	Professor
Phone:	(513) 558-7224
E-mail:	sohaib.khan@uc.edu

Education/Credentials:

M. Phil. (Biochemistry): Aligarh University, 1970
PhD (Biochemistry): Aligarah University, 1974
Fellowship (Moleculary Biology): Tata Institute of Fundamental Research, 1975
Fellowship (Cancer Biology): Rosewell Park Institute, 1979

Interest:

Hormonal Carcinogenesis

Current Research:

Estrogen-signaling and oncogene-mediated breast cancer development

Professional Affiliation:

Endocrine Society
Society for Biology of Reproduction
Sigma Xi

Member, Editorial Board, Steroids, 2002-present

Ad hoc Reviewer: J. Biological Chemistry; Endocrinology; Cancer Research; Gene, J. Endocrinology; Molecular and Cellular Endocrinology; Placenta; Molecular Pharmacology; Environmental Health Perspectives; J. Molecular and Cellular Cardiology; J. Pharmacology & Experimental Therapeutics; and Biology of Reproduction; Mutation Research; Oncogene

Recent Awards/Honors:

NIH/NCI Young Investigator Award, 1978-1981
Inaugural Faculty Achievement Award, University of Cincinnati, 1994
Chair, Organizing Committee, Jensen Symposium on Nuclear
Receptors, 2003

Selected Publications:

Recent publications include:

Yong, Y., Chirgadze, N.Y., Briggs, S.L., Khan, S, Jensen, E.V. and Burris, T.B. �A Second Binding Site for Hydroxy- Tamoxifen within the Coactivator Binding Groove of Estrogen Receptor �, Proc. Natl. Acad. Sci. USA 103: 9908 � 9911.

Rayala, SK, Talukder, AH, Seetharaman, B. Tharakan, R., Barnes, CJ, Wang, R-N, Aldaz, M., Khan, S. and Kumar, R. �PAK1 Regulation of Estrogen Receptor-alpha Activation Linked with Serine-118 Phosphorylation� Cancer Research 66: 1697-1701.

Ingraham, SE, Lynch, RA, Surti, U., Khan, SA, Menon, AG and Lepont, P. �HMGA2 in t(12;14) (q15;q24.1) Uterine Leiomyoma� , MUTATION RESEARCH.

Yang, J, Singleton, D. and Khan, S. �The F-domain of Estrogen receptor-alpha inhibits ligand induced receptor dimerization�, Endocrinology.

Feng, Y., Manka, D., Wagner, K-U and Khan, S.,�Mammary Epithelial Estrogen Receptor-a is required for mammary gland development and lactogenesis.�

MEDIA INTERVIEWS

To set up a media interview, please contact Amanda Harper at (513) 558-4657 during normal business hours (M-F, 8:30 a.m. to 5:30 p.m.). After hours, contact Harper at (513) 604-3308 or call (513) 558-4553 to be directed to the on-call public information officer.

RELATED INFORMATION

keywords: Sohaib Khan, cancer and cell biology, breast cancer, estrogen receptor gene, knock-out gene model, estrogen

Image: Sohaib Khan, PhD

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