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Fact Sheets
Date: 12/10/12
UC Early Stage Drug Development Program

Media Contact
To arrange interviews or learn more about the UC Early Stage Drug Development Program, please contact Amanda Harper directly at (513) 558-4657.


John Morris, MD

Director, Experimental Drug Trials Program

Professor, Hematology Oncology

UC College of Medicine

UC Barrett Cancer Institute at University Hospital

Telephone: (513) 584-7698 or 866-724-CURE (2873)



Alison Kastl

Director of Clinical Trials

UC Cancer Institute

Telephone: (513) 584-0436



About the Early Stage Drug Development Program

The UC Early Stage Drug Development Program is a phase-1 clinical trial unit based at the University of Cincinnati Cancer Institute. Led by John Morris, MD, the center offers discovery-driven new cancer treatment options only available in an experimental (phase-1) clinical trial setting.


Phase-1 clinical research trials are the first step in moving tested scientific concepts from the laboratory bench to bedside. Phase-1 trials are intended to evaluate safe dosages, method of administration (oral or injection) and frequency. Trials typically include less than 50 people and therapy is administered in a hospital setting where the patient can be monitored 24/7 by the attending physicians and support staff. 


Trials are available for patients with advanced, solid cancerous tumors that have failed standard medical therapies. Protocols are evaluated by the Internal Review Board for scientific content, safety and ethical considerations prior to implementation and throughout the trialís conclusion.


The UC Early Drug Development Program is part of the Cincinnati Cancer Center, a joint cancer program involving the UC College of Medicine, Cincinnati Childrenís Hospital Medical Center and UC Health. The collaborative initiative brings together interdisciplinary research teams of caring scientists and health professionals to research and develop new cures, while providing a continuum of care for children, adults and families with cancer.


Referral Process

For information on referring a patient to the phase-1 clinical trials unit, call 513-584-7698 or toll free at 866-724-CURE.


Clinical Partners

University of Cincinnati Medical Center (formerly University Hospital)

  • Three-bed dedicated inpatient hematology oncology care unit for administration of phase-1 clinical trial therapies
  • 24/7 medical coverage by board-certified oncology physicians and experienced nursing staff
  • Dedicated symptom management clinic as well as on-site nutrition, pastoral and rehabilitation services
  • Advanced on-site imaging services, including dynamic computed tomography (CT), dynamic contrast-enhanced magnetic resonance imaging and combination positron emission testing/CT scans


UC Health Barrett Center

  • Outpatient care facility for short- and long-term follow-up clinical care located on the UC Academic Health Center medical campus near downtown
  • Access to sophisticated radiation oncology treatment systems, including 3D and IMRT image-guided radiation therapy, and on-site private chemotherapy units


Research Partners

The scientific content of each research protocol is based on interactive collaboration with diverse basic scientists from the UCís cancer and  cell biology department, located at the Vontz Center for Molecular Studies,  as well as scientists with UCís Metabolic Diseases Institute, UCís Center for Imaging Research and other laboratories based in other UC laboratories, including molecular genetics, biochemistry and microbiology. A specific focus is given to the development of new biomarkers and cognitive analysis to determine individualized therapies.


Community Partners

American Cancer Society, Cincinnati Hope Lodge

The Musekamp Cincinnati Hope Lodge offers a cost-free comfortable, home-like environment for cancer patients traveling to Cincinnati for care. Adults with cancer may arrange for themselves and up to two caregivers to stay at the Hope Lodge through a referral process involving their Cincinnati-area physician, social worker or nurse. The lodge provides:  

  • Kitchen areas where families can cook their own meals,
  • Comfortable rooms with private bathrooms and space for both cancer patients and their caregivers, and
  • An on-site chapel, exercise room and library  

Financial Counseling

For questions about billing and insurance related to phase-1 clinical trial care, Tanya Green the UC Health Barrett Center at 513-584-3464. 

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