Cincinnati--The University of Cincinnati and Cincinnati Children's
Hospital Research Foundation today signed an agreement with Celera
Genomics in Rockville, Maryland to access Celera's databases of genomic
information from the mouse, human and fruit fly. Celera is the company
that headed the private effort to decode the human genome. A few weeks
ago, scientists from Celera and from the publicly funded Human Genome
Project announced they had successfully mapped the human genetic code.
3-year subscription agreement with Celera will provide UC researchers
access to the Celera Discovery System, which includes a comprehensive
set of bioinformatics systems and tools for viewing, browsing and
analyzing genomic information.
"Access to Celera's focused
databases by collaborating investigators of the Cincinnati Children's
Hospital Research Foundation and the University of Cincinnati will
represent a powerful complement to the outstanding work that is being
done by the worldwide Human Genome Project," said Robert F. Highsmith,
PhD, associate dean and director of research and graduate education, UC
College of Medicine. "We anticipate that the Celera resources will
allow us to gain insight into the genes responsible for diseases of
children and adults."
"The Medical Center is committed to
building our biotechnology capabilities," said Donald C. Harrison, MD,
senior vice president and provost for health affairs at UC. "The
announcement that scientists have substantially decoded the human
genome places genetic research on a fast track to develop new
approaches for preventing and treating many diseases. This is the
frontier of where the entire field of life sciences is going, and we
want University of Cincinnati to be on the front edge of the wave."
subscription agreement gives UC researchers access to four databases
developed by Celera. All four of Celera's databases include Celera
proprietary information as well as publicly available data.
the Celera Human Gene Index contains the set of human genes derived
from the EST (expressed sequence tags) programs. Second, Celera's Human
Genome Database is expected to provide the complete sequence of the
human genome and the entire collection of human genes with links to
associated biological and disease information. Third, the Drosophila
Genome Database provides the genome shotgun sequencing strategy. The
Drosophila genome database is extensively annotated with gene, protein
and biological information. Fourth, the Mouse Genome Database being
generated by Celera should allow for comparative analysis with the
human genome that may be especially significant for the identification
of genes and gene regulatory regions of importance to understanding
University of Cincinnati is a nationally
recognized leader in many areas of basic genetic research including
cancer, cardiopulmonary, neurobehavioral medicine, and perinatal and
early child development. UC researchers work across disciplines to
discover the causes and potential cures for diseases such as cystic
fibrosis, asthma, heart disease, neurological diseases, and cancer.